Reward-stress Link Points To New Targets For Treating Addiction

Investigators have discovered a functional link between reward and stress. They found that dopamine — the brain’s chief reward signal — works through corticotrophin-releasing factor — the brain’s main stress signal — to increase the activity of a brain region involved in addiction relapse. The findings, reported in the Journal of Neuroscience, point to new potential targets for treating alcohol and drug abuse — particularly the problem of relapse.

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