Research: impulsive rats quicker to do cocaine

Rats who rank high in impulsivity — the abstract doesn’t make clear how that was measured — are more likely to self-administer intravenous cocaine than their less impulsive peers, a group of scientists at Cambridge University has found. The study, led by Jeffrey W. Dalley, is significant because it found that the impulsive rats had a substandard set of dopamine receptors before being exposed to cocaine, thus supporting the hypothesis that dopamine receptor deficiency is a precondition, rather than a result, of chronic stimulant consumption. The study appears in the March 2 issue of Science. Abstract.While the study sheds light on stimulant use, this model will not transfer so easily to other drug use profiles, particularly opiates and depressants such as alcohol. (Source: New Recovery)

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