Increasing the brain level of receptors for dopamine, a pleasure-related chemical, can reduce use of cocaine by 75 percent in rats trained to self-administer it. Earlier research had similar findings for alcohol intake. Treatments that increase levels of these chemicals — dopamine D2 receptors — may prove useful in treating addiction.
Gene Therapy For Addiction: Flooding Brain With ‘Pleasure Chemical’ Receptors Works On Cocaine, As On Alcohol
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